Location: epiphysis - metaphysis - diaphysis-Epiphysis
Only a few lesions are located in the epiphysis, so this could be an important finding.
1-In young patients it is likely to be either a chondroblastoma or an infection.
2-In patients over 20, a giant cell tumor has to be included in the differential diagnosis.
3-In older patients a geode, i.e. degenerative subchondral bone cyst must be added to the differential diagnosis.
4-Look carefully for any signs of arthrosis.
-Metaphysis
NOF, SBC, CMF, Osteosarcoma, Chondrosarcoma, Enchondroma and infections.
-Diaphysis
Ewing's sarcoma, SBC, ABC, Enchondroma, Fibrous dysplasia and Osteoblastoma.
-Differentiating between a diaphyseal and a metaphyseal location is not always possible. Many lesions can be located in both or move from the metaphysis to the diaphysis during growth.Large lesions tend to expand into both areas.
http://www.radiologyassistant.nl/en/494e15cbf0d8d
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