Glioblastoma Multiforme on CT Scan

http://eradiology.bidmc.harvard.edu/Classics/item.aspx?section=Neuroimaging&labelpk=84a3cf36-44c2-4370-9522-50369eb830e3&pk=672b8da7-2a8d-43a2-a608-7fef8194b9bb

Findings

• The CT scan shows a large oval mass in the right frontal lobe with surrounding edema.
• There is a leftward midline shift and compression of the right lateral and third ventricles.

Discussion

There is a differential for low-attenuation supratentorial lesions on CT as well as for corpus callosum edema. This patient has glioblastoma multiforme, the most common primary brain malignancy in adults (20% of all primary brain tumors). MRI is more sensitive than CT for detecting brain tumors. CT is superior for detecting calcifications within the lesion.

Glioblastoma Multiforme on CT Scan

http://eradiology.bidmc.harvard.edu/Classics/item.aspx?section=Neuroimaging&labelpk=84a3cf36-44c2-4370-9522-50369eb830e3&pk=672b8da7-2a8d-43a2-a608-7fef8194b9bb

Findings

• The CT scan shows a large oval mass in the right frontal lobe with surrounding edema.
• There is a leftward midline shift and compression of the right lateral and third ventricles.

Discussion

There is a differential for low-attenuation supratentorial lesions on CT as well as for corpus callosum edema. This patient has glioblastoma multiforme, the most common primary brain malignancy in adults (20% of all primary brain tumors). MRI is more sensitive than CT for detecting brain tumors. CT is superior for detecting calcifications within the lesion.

GBM in a 49-year-old man. A, Axial T2-weighted image demonstrates a large right heterogeneous hemorrhagic mass with areas of necrosis (black arrow). B, Axial susceptibility gradient echo image demonstrates variable low signal intensity within the tumor, which confirms the presence of the blood products (white arrow) C, Axial enhanced Tl-weighted image. Note second right frontal lobe-enhancing lesion representing multifocal involvement (open arrow). (Click to magnify figure)

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Glioblastoma multiforme. A, Axial FLAIR and T2-weighted images demonstrate a large right temporal lobe mass with extensive signal abnormality extending across the splenium of the corpus callosum. There is also significant mass effect with right uncal herniation. The right temporal horn is trapped (white arrow). B, Axial and coronal enhanced Tl-weighted images show thick irregular enhancement. (Click to magnify figure)

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