small zone of transition

Small zone of transition
- A small zone of transition results in a sharp, well-defined border and is a sign of slow growth.
-A sclerotic border especially indicates poor biological activity.
-In patients <> 30years, and particularly over 40 years, despite benign radiographic features, metastasis or plasmacytoma also have to be considered
On the above three bone lesions with a narrow zone of transition. Based on the morphology and the age of the patients, these lesions are benign. Notice that in all three patients, the growth plates have not yet closed.
-In patients > 40 years metastases and multiple myeloma are the most common bone tumors.
-Metastases under the age of 40 are extremely rare, unless a patient is known to have a primary malignancy. Metastases could be included in the differential diagnosis if a younger patient is known to have a malignancy, such as neuroblastoma, rhabdomyosarcoma or retinoblastoma.


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