Osteoid matrix-Mineralization in osteoid tumors can be described as a trabecular ossification pattern in benign bone-forming lesions and as a cloud-like or ill-defined amorphous pattern in osteosarcomas. Sclerosis can also be reactive, e.g. in Ewing sarcoma or lymphoma.
left
Cloud-like bone formation in osteosarcoma. Notice the aggressive, interrupted periosteal reaction (arrows).
right Trabecular ossification pattern in osteoid osteoma. Notice osteolytic nidus (arrow).
http://www.radiologyassistant.nl/en/494e15cbf0d8d#a4b331e94d0f15
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