EG

- is a non-neoplastic proliferation of histiocytes and is also known as Langerhans cell histiocytosis.

-It should be included in the differential diagnosis of any sclerotic or osteolytic lesion, either well-defined or ill-defined, in patients under the age of 30.

-The diagnosis EG can be excluded in age > 30.

-EG is usually monostotic, but can be polyostotic.

- left

Osteolytic lesion arising from the neurocranium with associated soft tissue swelling.

middle

Mixed lytic-sclerotic lesion, not well-defined with solid periosteal reaction.

right

Sharply defined osteolytic lesion of the skull. There is no 'button sequestrum', which is more or less pathognomonic.Discriminator: Must be under age 30.

http://www.radiologyassistant.nl/en/4bc6176e56228